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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T13386 | Zandelisib | PI3K | |
Zandelisib is an inhibitor of phosphatidylinositol 3-kinase (PI3K)(p110δ, IC50 of 3.5 nM), and with antineoplastic activity. | |||
T2616 | PIK-93 | PIK 93 | ATM/ATR , DNA-PK , Virus Protease , PI3K , Carbonic Anhydrase , PI4K , mTOR , HSV |
PIK-93 is the first potent, synthetic PI4K inhibitor with IC50 of 19 nM; inhibits PI3Kα with IC50 of 39 nM. | |||
T12469 | PI4KIIIbeta-IN-9 | PI3K , PI4K | |
PI4KIIIbeta-IN-9 is a potent inhibitor of PI4KIIIβ(IC50 of 7 nM). . | |||
T4079 | LY-294002 hydrochloride | SF 1101,LY 294002,NSC 697286 | PI3K |
LY-294002 hydrochloride (NSC 697286) is a synthetic molecule inhibitor of PI3Kα/δ/β (IC50: 0.5/0.57/0.97 μM, in cell-free assays); more stable than Wortmannin in solution, and also is a blocker of autophagosome formation... | |||
T19840 | GSK-F1 | PI4KA inhibitor-F1 | PI4K |
GSK-F1 (PI4KA inhibitor-F1) is a novel potent PI4KA inhibitor. | |||
T28416 | PIK-108 | PIK 108,PIK108 | PI3K |
PIK-108 is an allosteric inhibitor of phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunits β and δ (PI3Kβ/δ). | |||
T1999 | Taselisib | RG-7604,GDC-0032 | PI3K , Carbonic Anhydrase |
Taselisib (GDC-0032) is an orally bioavailable inhibitor of the class I phosphatidylinositol 3-kinase (PI3K) alpha isoform (PIK3CA), with potential antineoplastic activity. | |||
T12365 | PARP/PI3K-IN-1 | PARP , PI3K | |
PARP/PI3K-IN-1 is a novel dual poly (ADP-ribose) polymerase (PARP) and phosphatidylinositol 3-kinase (PI3K) dual inhibitor with anticancer, antitumour and antiproliferative activities for the study of breast, pancreatic ... | |||
T16528 | PI-828 | LY 294002, 4gamma-NH2 | Casein Kinase , PI3K |
PI-828 is a phosphatidylinositol 3-kinase (PI3K) inhibitor, which is widely used to study the physiological function of PI3K and also promotes stem cell differentiation into mesoderm. | |||
T3399 | Psoralidin | Others , Estrogen/progestogen Receptor , Reactive Oxygen Species , Lipoxygenase , Gamma-secretase , Akt , COX , Antibacterial | |
Psoralidin inhibits Akt phosphorylation and phosphatidylinositol 3-kinase activation and transcriptionally. Psoralidin possesses anticancer and chemopreventive properties. | |||
T6168 | ZSTK474 | PI3K , Autophagy | |
PI3K Inhibitor ZSTK474 is an orally available, s-triazine derivative, ATP-competitive phosphatidylinositol 3-kinase (PI3K) inhibitor with potential antineoplastic activity. | |||
T1861 | Omipalisib | GSK458,GSK2126458 | PI3K , mTOR , Autophagy |
Omipalisib (GSK2126458) is a small-molecule pyridylsulfonamide inhibitor of phosphatidylinositol 3-kinase (PI3K) with potential antineoplastic activity. | |||
T67703 | MTOR inhibitor 9b | mTOR | |
mTOR inhibitor 9b is an enzyme inhibitor of protein kinase mTOR he phosphatidylinositol 3-kinase PIK3CA with IC50s of 0.76 nm and 1.262 µM, respectively.mTOR inhibitor 9b possesses anticancer activity and can be used to ... | |||
TN2019 | Orobol | 3'-Hydroxygenistein,3’,4’,5,7-tetrahydroxy-isoflavon | BCL , Caspase , PI3K |
Orobol (3’,4’,5,7-tetrahydroxy-isoflavon) is an inhibitor of tyrosine-specific protein kinase and phosphatidylinositol turnover. Orobol inhibits PI3K isoforms with IC50s of 3.46-5.27 μM for PI3K α/β/γ/K/δ. Orobol exhibit... | |||
T4S21320 | ISOGINKGETIN | 4',4'''-Dimethylamentoflavone | MMP , Others |
1. ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion with potency comparable to that of rosiglitazone, a known modulator of adiponecti... | |||
T36083 | DS-7423 | PI3K , mTOR | |
DS-7423 is a dual PI3K and mTOR inhibitor, with IC50 values of 15.6 nM, 34.9 nM for PI3Kα and mTOR, respectively. DS-7423 possesses anti-tumor activity[1][2]. DS-7423 increases TP53 expression, the level of p-TP53 on Ser... | |||
T67702 | MTOR inhibitor 9d | PI3K , mTOR | |
mTOR inhibitor 9d is a dual inhibitor of the protein kinases mTOR and PI3K with an mTOR IC50 value of 0.31 nm, and can be used for the treatment of leukemia, skin cancer, breast cancer, lung cancer and colon cancer. | |||
T69912 | AS2541019 | ||
AS2541019 is a selective Phosphatidylinositol-3-kinase p110δ (PI3Kδ) inhibitor. | |||
T71798 | Demethoxyviridiol | ||
Demethoxyviridiol is a mycotoxin that inhibits phosphatidylinositol 3-kinase (PI3K). | |||
T24637 | PI3K inhibitor C 96 | PI3K IN C96,PI3K-IN-C96 | |
PI3K inhibitor C 96 is an inhibitor of phosphatidylinositol 3-kinase. It shows effective activity against multiple myeloma in vitro and in vivo. |